Recombinatie Bax monoklonaal antilichaam

The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.

Bax

Q07812

Human; Mouse; Rat

Recombinant Human Bax protein

BCL2L4bcl2-L; Bcl-2-like protein; BCL2L; Bcl2-L; BAX; BCL2L4; apoptosis regulator BAX; Bcl2-L-4; BCL2L4bcl2-L-4; BCL2-associated X protein; Bcl-2-like protein 4; BAXA; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; Bax-protein; BCL2 associated X protein; BCL2 associated X protein omega; BCL2 associated X protein transcript variant delta2; Bcl-2-like protein 4 (Bcl2-L-4) ; membrane isoform alpha

10A11

Unconjugated

WB; IHC

Cell Biology; Metabolism; Cancer; Kits; Lysates; Other

Protein A

0.2 mg/mL

IHC 1:2000-1:5000; WB 1:1000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/MyINikdN

21 kDa

21 kDa

IgG, κ