Recombinatie Bcr monoklonaal antilichaam

Break point cluster region protein (Bcr) is encoded by the Bcr gene. The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine / threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia.

Bcr

P11274

Human; Rat

Recombinant human Bcr fragment

Renal carcinoma antigen NY-REN; BCR; ALL; BCR1; CML; D22S11; D22S662; PHL; Breakpoint cluster region; Renal carcinoma antigen NY-REN-26; bcr; BCR1; Breakpoint cluster region; CML; D22S11; D22S662; PHL; Renal carcinoma antigen NY-REN-26

A591

Unconjugated

WB; IHC

Signal Transduction; Cancer

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/UCKmRhAC

160 kDa

160 kDa

IgG, κ