Recombinatie Bim Monoklonale Antilichaam

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3) . It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Bim

O43521

Human; Mouse; Rat

Recombinant Human Bim protein

Bcl-2-like protein; BCL2L; Bcl2-L; BAM; BIM; BOD; BCL2L11; Bcl2-interacting mediator of cell death; Bcl2-L-11; Bcl-2-like protein 11; BIML; BimEL

4B11

Unconjugated

WB; IHC

Cell Biology; Neuroscience; Immunology; Signal Transduction; Cancer; Metabolism

Protein A

0.2 mg/mL

WB 1:2000-1:10000; IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/sfM0cVO6

22 kDa

22 kDa

IgG, κ