Recombinatie BMP-4 monoklonaal antilichaam

Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932]; also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia) . In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies., Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair., online information:Bone morphogenetic protein 4 entry, similarity:Belongs to the TGF-beta family., subunit:Homodimer; disulfide-linked (By similarity) . Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD., tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.

BMP-4

P12644

Human

Recombinant Human BMP-4 protein

OFC; DVR; MGC; ZGC; Bone morphogenetic protein; zbmp; MCOPS; BMP; BMP4; BMP2B; BMP2B1; MCOPS6; OFC11; ZYME; BMP 2B; BMP 4; BMP-2B; BMP-4; Bone morphogenetic protein 2B; Bone morphogenetic protein 4; MGC100779; zbmp-4; zgc:100779; DVR4; BMP-4

9B8

Unconjugated

IHC

Cardiovascular; Signal Transduction; Stem Cells; Cancer; Developmental Biology

Protein A

0.2 mg/mL

IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/gt18wi8I

IgG, κ