Recombinatie BOB-1 monoklonaal antilichaam

Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator.

BOB-1

Q16633

Human

Recombinant human BOB-1 fragment

BOB; POU2AF; OBF; POU2AF1; BOB1; OBF-1; OBF1; OCAB; POU2AF1; BOB1; OBF-1; OBF1; OCAB

A144

Unconjugated

WB; IHC

Immunology; Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/e6ZEdNgG

27 kDa

35 kDa

IgG, κ