Recombinatie BRAT1 monoklonaal antilichaam

The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex) . The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.

BRAT1

Q6PJG6

Human

Recombinant Human BRAT1 protein

BRAT; BAAT; C7orf; BRAT1; BAAT1; C7orf27; RMFSL

4B12

Unconjugated

WB

Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

WB 1:1000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/HM0DodyQ

90 kDa

90 kDa

IgG, κ