Recombinatie c-erbB-3 / HER-3 monoklonaal antilichaam

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5) . Involved in the regulation of myeloid cell differentiation.

C-erbB-3/HER-3

P21860

Human

Recombinant human c-erbB-3/HER-3 fragment

HER; LCCS; Proto-oncogene-like protein c-ErbB; Tyrosine kinase-type cell surface receptor HER; MDA-BF; p180-ErbB; p45-sErbB; p85-sErbB; ERBB3; ErbB-3; HER3; LCCS2; MDA-BF-1; c-erbB-3; c-erbB3; erbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; EEBB3

A215

Unconjugated

IHC

Signal Transduction; Cancer

Protein A purified

1 mg/mL

IHC 1:100-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/H75OfUB8

IgG, κ