Recombinatie CBP monoklonaal antilichaam

CREB-binding protein (CREBBP/CBP), encoded by the human CREBBP gene, is a transcriptional co-activator. CREBBP functions through interactions with transcription factors, mediated by one or more domains: the nuclear receptor interaction domain (RID), the KIX domain (CREB and MYB interaction domain), the cysteine/histidine regions (TAZ1/CH1 and TAZ2/CH3), and the interferon response binding domain. The KIX, TAZ1, and TAZ2 domains of CREBBP bind tightly to the 9aaTADs, the nine amino acid transactivation domains within the tumor suppressor protein p53, thereby influencing its transcriptional activity.

CBP

Q92793

Human

Synthetic peptide derived from the human CBP protein

CREBBP; CBP; KAT3A; RSTS; RSTS1; CREB binding protein; CREB-binding protein; Cyclic AMP responsive enhancer binding protein; RTS; Rubinstein Taybi syndrome

A152

Unconjugated

WB; IF

Epigenetics and Nuclear Signaling; Microbiology; Stem Cells; Cancer; Metabolism

Protein A purified

1 mg/mL

WB 1:1000-1:3000; IF 1:100-1:200

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/wMW4aOX4

300 kDa

300 kDa

IgG, κ