Recombinatie CBX2- monoklonaal antilichaam

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) . Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression.

CBX2

Q14781

Human; Rat; Mouse

Synthetic peptide derived from the human CBX2 protein

CBX; CDCA; SRXY; CBX2; CDCA6; M33; SRXY5

A153

Unconjugated

WB

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

WB 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/b722gjlZ

25 kDa

25 kDa

IgG, κ