Recombinatie CD278 / ICOS monoklonaal antilichaam

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

CD278/ICOS

Q9Y6W8

Human

Recombinant human CD278/ICOS fragment

CVID; ICOS; AILIM; CD278; CVID1; activation-inducible lymphocyte immunomediatory molecule; Inducible T-cell costimulator

A168

Unconjugated

IHC

Immunology

Protein A purified

1 mg/mL

IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/u4RFUMgP

IgG, κ