Recombinatie CD41 monoklonaal antilichaam

Integrin α-IIb/β-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bond-connected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness.

CD41

P08514

Human

Recombinant human CD41 fragment

HPA; PPP1R; ITGA2B; BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93; GPalpha Iib; Integrin alpha-Iib; Platelet membrane glycoprotein Iib; ITGAB; &alpha-IIb integrin-n; BDPLT16; alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex; alpha subunit; antigen CD41; antigen CD41) ; form 2; Integrin; Integrin alpha 2b; Integrin alpha IIb; Integrin alpha-IIb light chain; integrin αIIbβ3; ITA2B; platelet fibrinogen receptor; platelet glycoprotein IIb of IIb/IIIa complex; platelet specific antigen BAK

A173

Unconjugated

WB

Cardiovascular; Immunology; Signal Transduction; Stem Cells

Protein A purified

1 mg/mL

WB 1:500-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/N1OiSlRh

113 kDa

128 kDa

IgG, κ