Recombinatie CD70 monoklonaal antilichaam

CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is normally expressed on medullary thymic epithelial cells. Its expression is induced on activated lymphoid cells (B cells, T cells, and NK cells) and dendritic cells. CD70 is a ligand for CD27, a co-stimulatory receptor that plays an important role in T cell activation and proliferation. CD70 overexpression has been reported in various tumors such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma and it’s being actively pursued as a therapeutic target.

CD70

P32970

Human

Recombinant human CD70 fragment

Tumor necrosis factor ligand superfamily member; TNFSF; CD70; CD27-L; CD27L; CD27LG; TNFSF7; TNLG8A; CD27 ligand; CD70 antigen; Tumor necrosis factor ligand superfamily member 7; Ki-24; CD27L; TNFSF7; CD 27L; CD 70; CD27 L; CD27 LG; CD70 molecule; Ki 24 antigen; Ki24 antigen; member 7; sCD27 Ligand; soluble CD27 Ligand; Surface antigen CD70; TNFSF 7; Tumor necrosis factor (ligand) superfamily

A550

Unconjugated

WB

Immunology; Cancer; Stem Cells

Protein A purified

1 mg/mL

WB 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/pez8EJFj

23 kDa

27,54,81 kDa

IgG, κ