Recombinatie CD79a monoklonaal antilichaam

Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

CD79a

P11912

Human

Recombinant human CD79a fragment

CD79A; IGA; MB-1; CD79a molecule; CD79A antigen; MB1; MB1; Ig&alpha

A181

Unconjugated

WB; IHC

Immunology; Cancer; Stem Cells

Protein A purified

1 mg/mL

WB 1:1000-1:5000; IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/upmQ8KJh

25 kDa

44-48 kDa

IgG, κ