Recombinatie CEACAM6 monoklonaal antilichaam

Carcinoembryonic antigen (CEA) -related cell adhesion molecule 6 (CEACAM6) is a member of the CEA-related cell adhesion molecule (CEACAM) family. CEACAMs bind to themselves and other family members to carry out numerous cellular functions, including proliferation, signaling, differentiation, tumor suppression, and survival. CEACAM6 is a single-chain, glycosylphosphatidylinositol (GPI) -anchored, highly glycosylated protein that is normally expressed on epithelial cells and granulocytes. CEACAM6 mediates homophilic and heterophilic cell adhesion with other CEA-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils, and plays a role in neutrophil adhesion to cytokine-activated endothelial cells. High levels of CEACAM6 expression are also observed in several different cancers. In cancer, CEACAM6 promotes tumor progression, migration, invasion, and metastasis, and therefore is considered a target for therapeutic intervention.

CEACAM6

P40199

Human; Rat; Mouse

Peptide. This information is proprietary to PTMab.

CEACAM; CEACAM6; CD66c; CEAL; NCA; Carcinoembryonic antigen related cell adhesion molecule 6; Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen) ; Carcinoembryonic antigen-related cell adhesion molecule 6; CD 66c; CD66c antigen; CEA LIKE PROTEIN; CEACAM 6; CEAM6; MGC93832; Non specific cross reacting antigen; Non-specific crossreacting antigen; Normal cross reacting antigen; Normal cross-reacting antigen

A750

Unconjugated

WB; IHC

Tags & Cell Markers; Immunology; Cancer

Protein A purified

1 mg/mL

WB 1:1000; IHC 1:200

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/9rFLw4vN

37 kDa

40-100 kDa

IgG, κ