Recombinatie CREBBP monoklonaal antilichaam

CREB binding protein (CREBBP) Homo sapiens This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS) .

CREBBP

Q92793

Human; Mouse; Rat

Recombinant Human CREBBP protein

CREBBP; CBP; KAT3A; RSTS; RSTS1; CREB binding protein; CREB-binding protein; Cyclic AMP responsive enhancer binding protein; RTS; Rubinstein Taybi syndrome

7A16

Unconjugated

WB

Epigenetics and Nuclear Signaling; Microbiology; Stem Cells; Cancer; Metabolism

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/NtzqSEpO

300 kDa

300 kDa

IgG, κ