Recombinatie Cycline E1 monoklonaal antilichaam

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

Cyclin E1

P24864

Human; Mouse; Rat

Recombinant Human Cyclin E1 protein

G1/S-specific cyclin-E; pCCNE; cyclin E; CCNE1; CCNE; pCCNE1; cyclin E1; cyclin E variant ex5del; cyclin E variant ex7del; Cyclin Es; Cyclin Et; CyclinE; G1/S specific cyclin E; G1/S-specific cyclin-E1

6G15

Unconjugated

WB; IHC

Cell Biology; Epigenetics and Nuclear Signaling; Cancer

Protein A

0.2 mg/mL

IHC 1:400-1000; WB 1:1000-5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/t02TX7lI

47 kDa

47 kDa

IgG, κ