Recombinatie DNMT1 monoklonaal antilichaam

Dnmt1 is an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities.

DNMT1

P26358

Human

Recombinant human Dnmt1 fragment

MGC; CXXC; DNA methyltransferase; CXXC finger protein 9|DNA methyltransferase; ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1; CXXC finger protein 9|DNA methyltransferase 1; DNA methyltransferase 1; FLJ16293; MGC104992; ADCADN; AIM; CXXC9; DNA methyltransferase 1; DNMT; HSN1E; m.HsaI; MCMT; CXXC finger protein 9; CXXC-type zinc finger protein 9; DNA (cytosine 5) methyltransferase 1; DNA (cytosine-5) -methyltransferase 1; DNA methyltransferase HsaI; DNA methyltransferase M.HsaI.; DNA MTase; DNA MTase HsaI; DNMT 1; Dnmt1o; Met1; mMmul; MommeD2

A436

Unconjugated

WB; IHC; IF; IP

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:200-1:1000; IF 1:50; IP 1:25-1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/XMGudl0w

183 kDa

200 kDa

IgG, κ