Recombinatie DPP4 / CD26 monoklonaal antilichaam

DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding domain are located in the extracellular fragment. DPP4/CD26 is a multifunctional protein that exists in both a membrane bound form as well as an extracellular soluble form. As a peptidase, it removes N-terminal dipeptides sequentially from proteins with a proline or alanine as the penultimate P1 amino acid. DPP4/CD26 has been shown to cleave a wide range of substrates including GLP-1, BNP, etc. In addition to its peptidase activity, DPP4/CD26 interacts with multiple important cell surface ligands, such as adenosine deaminase, fibronectin, and IGF2 receptor to influence processes like T cell activation, cell migration and proliferation.

DPP4/CD26

P27487

Human; Rat; Mouse

Recombinant human DPP4/CD26 fragment

DPP; dipeptidylpeptidase; dipeptidyl-peptidase; dipeptidyl peptidase; T-cell activation antigen CD; adenosine deaminase complexing protein; DPP4; ADABP; ADCP2; CD26; DPPIV; TP103; Dipeptidyl peptidase IV; ADCP-2; dipeptidyl-peptidase 4; dipeptidyl peptidase 4; DPP IV; dipeptidylpeptidase 4; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV; Dipeptidyl peptidase IV (DPP IV) ; ADABP Protein; ADCP2 Protein; CD26 Protein; DPPIV Protein; Human; TP103 Protein

A680

Unconjugated

WB; IHC

Immunology; Cell Biology; Stem Cells; Cancer; Metabolism

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:200-1:500

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/oaA9kcJr

110 kDa

110 kDa

IgG, κ