Recombinatie eIF2α monoklonaal antilichaam

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) .

EIF2α

P05198

Human; Mouse; Rat

Recombinant Human eIF2α protein

EIF2S; EIF; EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A; EIF2S1; EIF 2; EIF 2 alpha; EIF 2A; EIF 2alpha; EIF2 alpha; eIF-2-alpha; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit 1 alpha; Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa; Eukaryotic translation initiation factor 2 subunit alpha; IF2A

5C3

Unconjugated

WB

Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/wrWk6Fda

36 kDa

36 kDa

IgG, κ