Recombinatie ELNE monoklonaal antilichaam

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN) . This gene is present in a gene cluster on chromosome 19.

ELNE

P08246

Human

Recombinant Human ELNE protein

SCN; ELA; Elastase; ELANE; ELA2; GE; HLE; HNE; NE; PMN-E; SCN1; Elastase-2; Medullasin; Neutrophil elastase; Bone marrow serine protease; Human leukocyte elastase; PMN elastase; Elastase 2; Elastase 2 neutrophil; Elastase neutrophil expressed; ELNE; Granulocyte derived elastase; Leukocyte elastase; Neutrophil expressed; PMN E; Polymorphonuclear elastase

5C7

Unconjugated

WB

Immunology; Microbiology; Signal Transduction; Cancer; Kits; Lysates; Other

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/L6SbH3wF

29 kDa

30 kDa

IgG, κ