Recombinatie EpA2 monoklonaal antilichaam

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway.

EphA2

P29317

Human

Recombinant human EphA2 fragment

ARCC; CTPP; EPHA; Ephrin type-A receptor; CTRCT; ARCC2; CTPA; CTPP1; CTRCT6; ECK; EPHA2; Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK; AW545284; EPH receptor A2; Myk2; Sek2; Sek-2

A213

Unconjugated

WB; IHC

Cardiovascular; Neuroscience; Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/BFA9MaDU

109 kDa

130 kDa

IgG, κ