Recombinatie ERK5 monoklonaal antilichaam

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) . It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

ERK5

Q13164

Human; Mouse; Rat

Recombinant Human ERK5 protein

BMK; MAPK; PRKM; ERK; MAPK7; BMK1; ERK4; ERK5; PRKM7; Big MAP kinase 1; BMK 1; BMK 1 kinase; BMK-1; BMK1 Kinase; EC 2.7.11.24; ERK 4; ERK 5; ERK-5; Extracellular signal regulated kinase 5; Extracellular signal-regulated kinase 5; MAP kinase 7; MAPK 7; Mitogen activated protein kinase 7; MITOGEN-ACTIVATED; Mitogen-activated protein kinase 7; MK07; OTTHUMP00000065906; OTTHUMP00000065907; PRKM 7; PROTEIN KINASE; ERK 5

5B13

Unconjugated

WB

Neuroscience; Signal Transduction

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/uYthz5xw

88 kDa

115 kDa

IgG, κ