Recombinatie FBX32 monoklonaal antilichaam

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

FBX32

Q969P5

Human; Mouse; Rat

Recombinant Human FBX32 protein

FBX; FBXO; FBXO32; Fbx32; MAFbx;4833442G10Rik; AI430017; Atrogin 1; ATROGIN1; Atrogin-1; Atrophy gene 1; F box only protein 32; F-box only protein 32; F-box protein 32; fbxo25; FLJ32424; MGC108443; MGC137646; MGC33610; Muscle atrophy F box; Muscle atrophy F box protein; Muscle atrophy F-box protein; FBX32

12G7

Unconjugated

WB

Cell Biology; Stem Cells; Cardiovascular

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/6n18V6dQ

42 kDa

42 kDa

IgG, κ