Recombinatie FBXW7 monoklonaal antilichaam

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination.

FBXW7

Q969H0

Human

Recombinant human FBXW7 fragment

FBX; CDC; FBXO; hCdc; FBW; SEL; FBXW7; AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; SEL-10; SEL10; hAgo; hCdc4; Archipelago; Archipelago homolog; DKFZp686F23254; Drosophila; Drosophila) ; E3 ubiquitin protein ligase; F box and WD 40 domain protein 7; F box and WD 40 domain protein 7 (archipelago homolog; F box and WD repeat domain containing 7; F box protein FBW7; F box protein FBX30; F box protein SEL 10; F box protein SEL10; F-box and WD repeat domain containing 7; F-box and WD-40 domain-containing protein 7; F-box protein FBX30; F-box/WD repeat-containing protein 7; FLJ16457; homolog of; Homolog of C elegans sel 10; Homolog of C.elegans sel10; S.cerevisiae; SEL 10

A220

Unconjugated

IHC; IF

Cell Biology; Cancer

Protein A purified

1 mg/mL

IHC 1:100-1:1000; IF 1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/9RCx0jUG

IgG, κ