Recombinatie FUMA monoklonaal antilichaam

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

PUMA

Q9BXH1

Human; Mouse; Rat

Recombinant Human PUMA protein

BBC; PUMA; BBC3; BBC 3; BBC3_HUMAN; BCL 2 binding component 3; BCL2 binding component 3; Bcl-2-binding component 3; JFY 1; JFY1; JFY-1; p53 up regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; p53 up-regulated modulator of apoptosis; PUMA alpha; PUMA/JFY1

4B14

Unconjugated

WB

Cell Biology; Signal Transduction; Cancer; Metabolism

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/3CA0HD1D

21 kDa

21 kDa

IgG, κ