Recombinatie GAD-65 / 67 monoklonaal antilichaam

GAD1 (glutamate decarboxylase 1) Homo sapiens This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

GAD-65/67

Q05329; Q99259

Human; Mouse; Rat

Recombinant Human GAD-65/67 protein

GAD; GAD2; GAD65;65 kDa glutamic acid decarboxylase; DCE 2; DCE2; GAD 2; GAD 65; GAD-2; GAD-65; Glutamate decarboxylase 2; Glutamate decarboxylase 2 (pancreas) ; Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa) ; Glutamate Decarboxylase 65; Glutamate decarboxylase 65 kDa isoform; Glutamic Acid Decarboxylase 2; Glutamic Acid Decarboxylase 65; MGC161605; MGC161607; GAD-65/67

12G12

Unconjugated

WB; IHC

Neuroscience; Metabolism

Protein A

0.2 mg/mL

IHC 1:200-1:1000; WB 1:10000-1:50000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/Vy3ZZ4P6

65 kDa,67 kDa

65 kDa,67 kDa

IgG, κ