Recombinatie GIRK2- monoklonaal antilichaam

GIRK2 is a member of G protein-coupled inwardly rectifying potassium channel family proteins (GIRKs) . GIRK family proteins allow potassium to flow into the cell and therefore control cellular excitability in the central nervous system, heart, and pancreas. Activation of most GIRK channels requires heterologous subunit assembly and the presence of ATP. GIRK2 is abundantly expressed in the brain, where it is involved in pain perception. It is also required for peripheral opioid-mediated analgesia. Additionally GIRK2 localizes to pancreatic β cells and regulates insulin secretion. Mutations in the KCNJ6 gene encoding GIRK2 are associated with Keppen-Lubinsky Syndrome, a rare disease characterized by severe developmental delay, facial dysmorphism, and intellectual disability.

GIRK2

P48542

Mouse

Peptide. This information is proprietary to PTMab.

Girk; Girk2; Kcnj7; W; Kcnj6

A688

Unconjugated

WB

Protein A purified

1 mg/mL

WB 1:2000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/tQjXkYxC

48 kDa

40, 48 kDa

IgG, κ