Recombinatie GOSR1 / GS28 monoklonaal antilichaam

Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14) . Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.

GOSR1/GS28

O95249

Human; Mouse

Recombinant human GOSR1/GS28 fragment

GOSR; GOLIM; GOS28/P; GOS; GOSR1; GOLIM2; GOS-28; GOS28; GOS28/P28; GS28; P28

A235

Unconjugated

WB; IHC; IF; FCM

Neuroscience; Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:50-1:100; IF 1:50; FCM 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/4Lk02DjP

29 kDa

29 kDa

IgG, κ