Recombinatie GRP94 monoklonaal antilichaam

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD) . Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.

GRP94

P14625

Human; Rat; Mouse

Recombinant human GRP94 fragment

HEL; TRA; GRP; HSP90B; HSP90B1; ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1; endoplasmin; ECGP; endoplasmin; GP96; GRP94; HEL35; HEL-S-125m; TRA1;90 kDa;94 kDa glucose regulated protein;94 kDa glucose-regulated protein; beta; Endothelial cell (HBMEC) glycoprotein; ENPL; ERp99; Glucose regulated protein 94kDa; gp96 homolog; GRP 94; GRP-94; Heat shock protein; Heat shock protein 90 kDa beta member 1; heat shock protein 90kDa beta (Grp94) ; Heat shock protein 90kDa beta member 1; member 1; Stress inducible tumor rejection antigen GP96; tumor rejection antigen (gp96) 1; Tumor rejection antigen 1; Tumor rejection antigen gp96; Tumor rejection antigen-1 (gp96)

A241

Unconjugated

WB; IF; IHC; IP

Tags & Cell Markers; Signal Transduction; Cancer; Metabolism

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50; IP 1:25-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/1MVXu3zl

94 kDa

100 kDa

IgG, κ