Recombinatie HRAS monoklonaal antilichaam
Gecertificeerd

Recombinatie HRAS monoklonaal antilichaam

Catalog #: AN300826L-01
Maat: 50 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100

Technische Specificaties

Background

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

Abbreviation

HRAS

UniProt

P01112

Host

• Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human HRAS protein

Target

RASH; Transforming protein p; H Ras; C-HA-RAS; C HA RAS; C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras; GTPase HRAS; HRAS; C BAS/HAS; C HA RAS1; H Ras 1; H RASIDX; Harvey rat sarcoma viral oncogene homolog; K ras; N ras; p19 H RasIDX protein; Transforming protein p21; vHa RAS; C HA RAS1; CTLO; H Ras 1; H RASIDX; HAMSV; Harvey rat sarcoma viral oncogene homolog; HRAS1; K ras; N ras; p19 H RasIDX protein; p21ras; RASH1; Transforming protein p21; vHa RAS; c H ras; c has/bas p21 protein; c ras Ki 2 activated oncogene; GTP and GDP binding peptide B; Ha Ras; Ha Ras1 proto oncoprotein; Ha-Ras; Harvey rat sarcoma viral oncoprotein; H-Ras-1; N-terminally processed; Ras family small GTP binding protein H Ras; Transformation gene oncogene HAMSV; v Ha ras Harvey rat sarcoma viral oncogene homolog; VH Ras

Clonality

• Monoclonal

• Recombinant

Clone

5B10

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Cell Biology; Tags & Cell Markers

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/vXh57Mdg

Calculated Molecular Weight

21 kDa

Observed Molecular Weight

21 kDa

Isotype

IgG, κ

Beschrijving

Recombinatie HRAS monoklonaal antilichaam Beschikbaar in 50 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamRecombinatie HRAS monoklonaal antilichaam
Categorie
Beschikbare grootte50 µL
CatalogusnummerAN300826L-01