Recombinatie IGF1 Multiklonaal antilichaamontvanger

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

IGF1 Receptor

P08069

Human

Recombinant Human IGF1 Receptor protein

JTK; IGF1R; CD221; IGFIR; IGFR; JTK13; CD221 antigen; IGF-1R; IGF-I R; IGF-I receptor; IGF-IR; insulin-like growth factor 1 receptor; IGF-1R

6A5

Unconjugated

WB; IHC

Signal Transduction; Cancer; Developmental Biology; Neuroscience; Cardiovascular; Metabolism

Protein A

0.2 mg/mL

IHC 1:100-200; WB 1:1000-5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/dF3ViTID

154 kDa

200 kDa

IgG, κ