Recombinatie iNOS monoklonaal antilichaam

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.

INOS

P29477

Human; Mouse

Recombinant human iNOS fragment

NOS; HEP-NOS; I-NOS; NOS2A; inducible; Inos; MAC-NOS; Inosl; Nitric oxide synthase; NOS type II; Nos2

A267

Unconjugated

IHC

Protein A purified

1 mg/mL

IHC 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/8MMqvrRx

IgG, κ