Recombinatie JNK2 monoklonaal antilichaam

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells.

JNK2

P45984

Human; Mouse; Rat

Recombinant Human JNK2 protein

MAPK; PRKM; JNK; MAPK9; JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; PRKM9; SAPK; SAPK1a; p54a; p54aSAPK; c Jun kinase 2; C Jun N terminal kinase 2; c-Jun N-terminal kinase 2; JNK 55; JNK2 alpha; JNK2 beta; Jun kinase; MAP kinase 9; MAPK 9; Mitogen activated protein kinase 9; mitogen-activated; Mitogen-activated protein kinase 9; MK09; Protein kinase; SAPK alpha; Stress activated protein kinase 1a; Stress-activated protein kinase JNK2

3P10

Unconjugated

WB

Signal Transduction; Cell Biology; Cancer; Immunology; Metabolism; Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/O0EDIYgn

48 kDa

46,54 kDa

IgG, κ