Recombinatie Ku80 monoklonaal antilichaam

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Ku80

P13010

Mouse

Recombinant human Ku80 fragment

KUB; XRCC; G22P; XRCC5; KARP-1; KARP1; KU80; KUB2; Ku86; NFIV; G22P2

A283

Unconjugated

IHC

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/RXwusD0I

IgG, κ