Recombinatie LRp6 monoklonaal antilichaam

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

LRP6

O75581

Human; Mouse

Recombinant Human LRP6 protein

LRP; ADCAD; STHAG; LRP6; ADCAD2; STHAG7; C030016K15Rik; FLJ90062; FLJ90421; LDL receptor related protein 6; Low density lipoprotein receptor related protein 6; Low-density lipoprotein receptor-related protein 6; LRP-6; OTTHUMP00000238979; OTTHUMP00000238980; OTTHUMP00000238982

11A1

Unconjugated

WB

Signal Transduction; Stem Cells; Cardiovascular; Neuroscience; Metabolism

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/QsF0odLV

180 kDa

210 kDa

IgG, κ