Recombinatie Lumican monoklonaal antilichaam

Lumican (LUM), a member of the small leucine-rich proteoglycan (SLRP) family, is one of the major extracellular components in interstitial collagenous matrices of the corneal stroma, aorta, skin, skeletal muscle, lung, kidney, bone, cartilage, and intervertebral discs. SLRPs constitute an important fraction of noncollagenous extracellular matrix proteins and have important effects on cell behavior. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and may exist as a glycoprotein in the connective tissues of other organs. Posttranslational modifications lumican goes through can increase its apparent molecular weight to 50-90 kDa. Lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation.

Lumican

P51884

Human; Rat; Mouse

Recombinant human Lumican fragment

LUM; LDC; SLRR2D; lumican; Keratan Sulfate Proteoglycan Lumican; KSPG Lumican; Lumican precursor

A552

Unconjugated

WB

Cancer; Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/1zHgzZkt

38 kDa

50-70 kDa

IgG, κ