Recombinatie MAO-A monoklonaal antilichaam

Monoamine oxidase A (MAO-A), a mitochondrial enzyme, catalyzes the degradation of monoamines. Studies show that increased expression of MAO-A promotes prostate cancer metastasis by activating the Shh-IL6-RANKL signaling network. In addition, MAO-A expression in adipose tissue macrophages is upregulated in aging, leading to the reduction of noradrenaline availability in adipose tissue. Decreased levels of noradrenaline contribute to the aging-related decline of catecholamine-induced lipolysis in adipocytes. Furthermore, sympathetic neuron–associated macrophages import and degrade norepinephrine via the transporter SLC6A2 and MAO-A, respectively, and thus contribute to obesity.

MAO-A

P21397

Human; Mouse

Recombinant human MAO-A fragment

MAOA; BRNRS; MAO-A

A611

Unconjugated

WB; IHC

Tags & Cell Markers; Neuroscience; Metabolism

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:50-1:200

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/FoulgmC8

60 kDa

60 kDa

IgG, κ