Recombinatie MDR1 monoklonaal antilichaam

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

MDR1

P08183

Human

Recombinant Human MDR1 protein

MDR; PGY; ABC; ABCB; P-glycoprotein; Phospholipid transporter ABCB; ATP-dependent translocase ABCB; ATP-binding cassette sub-family B member; ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1; P Glycoprotein; ABCB1; ATP-binding cassette sub-family B member 1; ATP-dependent translocase ABCB1; P-glycoprotein 1; Phospholipid transporter ABCB1; MDR-1; P-gp; gp170; ABC-B1; ATP binding cassette; Colchicin sensitivity; Doxorubicin resistance; member 1; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; sub family B (MDR/TAP)

5B3

Unconjugated

WB

Signal Transduction; Stem Cells; Cancer

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/H0b0HpdF

141 kDa

141 kDa

IgG, κ