Recombinatie MTAP monoklonaal antilichaam

MTAP is an enzyme essential for the salvage pathway for both adenine and methionine synthesis. MTAP catalyzes the cleavage of 5’-methylthioadenosine into adenine and 5-methylthio-D-ribose-1-phosphate. Adenine is then used to generate AMP whereas 5-methylthio-D-ribose-1-phosphate is converted into methionine. MTAP is expressed in all normal cells and tissues, although frequently lost in different human tumors including pancreatic adenocarcinoma, neuroendocrine tumors, non-small cell lung carcinoma and breast carcinoma, thereby implicating its potential function as a tumor suppressor.

MTAP

Q13126

Human; Mouse

Recombinant human MTAP fragment

HEL; MTAP; BDMF; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP; c86fus;5' methylthioadenosine phosphorylase;5''-methylthioadenosine phosphorylase; Epididymis luminal protein 249; HEL 249; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MTA phosphorylase; MTAPase; S methyl 5 thioadenosine phosphorylase; S methyl 5' thioadenosine phosphorylase; S-methyl-5''-thioadenosine phosphorylase

A519

Unconjugated

WB; IHC

Signal Transduction; Metabolism

Protein A purified

1 mg/mL

WB 1:1000-1:3000; IHC 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/y3q7WzLS

31 kDa

31 kDa

IgG, κ