Recombinatie NFkB-p100 monoklonaal antilichaam

NFKB2 (nuclear factor kappa B subunit 2) Homo sapiens This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) . The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

NFkB-p100

Q00653

Human; Mouse; Rat

Recombinant Human NFkB-p100 protein

CVID; H2TF; NFKB; NF-kB; p49/p; LYT; CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52; NFKB2; p105; NF-κB p100/p52

11A4

Unconjugated

WB

Signal Transduction; Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/qz8MG6kS

97 kDa

120 kDa

IgG, κ