Recombinatie Nibrin monoklonaal antilichaam

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Nibrin

O60934

Human; Mouse; Rat

Recombinant Human Nibrin protein

MGC; Cell cycle regulatory protein p; Nijmegen breakage syndrome protein; NBN; AT-V1; AT-V2; ATV; NBS; NBS1; P95; nibrin; AT V1; AT V2; Cell cycle regulatory protein p95; FLJ10155; MGC87362; NBS 1; Nijmegen breakage syndrome; Nijmegen breakage syndrome 1 (nibrin) ; Nijmegen breakage syndrome protein 1; p95 protein of the MRE11/RAD50 complex; ATV; AT-V1; AT-V2; NBS; NBS1; nibrin; P95; Nibrin

11A8

Unconjugated

WB; IHC

Epigenetics and Nuclear Signaling; Cancer

Protein A

0.2 mg/mL

IHC 1:200-1:1000; WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/oGINenrt

85 kDa

95 kDa

IgG, κ