Recombinatie NOX2 monoklonaal antilichaam

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) . In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

NOX2

P04839

Human; Mouse; Rat

Recombinant Human NOX2 protein

IMD; NOX; GP91; AMCBX; AMCBX2; CGD; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX; CYBB; beta polypeptide; CGD91-phox; CY24B; Cytochrome b 245; Cytochrome b (558) beta chain; Cytochrome b (558) subunit beta; Cytochrome b-245 heavy chain; Cytochrome b558 subunit beta; GP91 PHOX; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; p22 phagocyte B-cytochrome; P91 PHOX; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-phox

10F9

Unconjugated

WB

Immunology; Cancer; Metabolism

Protein A

0.2 mg/mL

WB 1:1000-5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/LKV6mLCs

65 kDa

65 kDa

IgG, κ