Recombinatie p40 monoklonaal antilichaam

Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.

P40

Q7Z6M1

Human

Recombinant human p40 fragment

RAB9P; RAB9P40; RABEPK;40 kDa Rab9 effector protein;8430412M01Rik;9530020d24rik; AV073337; bA65N13.1; C87311; DKFZp686P1077; OTTHUMP00000022126; OTTMUSP00000012898; OTTMUSP00000012899; OTTMUSP00000041318; p40; RAB9 effector p40; Rab9 effector protein with Kelch motifs; RABEK; RABEPK protein; RGD1310612; RP11 65N13.1; RP23-446N16.2

A677

Unconjugated

WB

Signal Transduction; Cell Biology

Protein A purified

1 mg/mL

WB 1:1000-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/ifZom07w

41 kDa

41 kDa

IgG, κ