Recombinatie Pi3 Kinase p110 delta monoklonaal antilichaam

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) belongs to Class I Phosphoinositide-3-kinase (PI3K) which phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides and uses ATP and PtdIns (4,5) P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3) . PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.

PI3 Kinase p110 delta

O00329

Human; Mouse

Recombinant human PI3 Kinase p110 delta fragment

IMD; PIK3CD; APDS; IMD14; P110DELTA; PI3K; p110D

A470

Unconjugated

WB

Signal Transduction; Immunology

Protein A purified

1 mg/mL

WB 1:1000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/FprLGPG0

119 kDa

119 kDa

IgG, κ