Recombinatie PLCG2 monoklonaal antilichaam

Phospholipase C-gamma2 (PLCG2) is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor.IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome.

PLCG2

P16885

Human

Recombinant human PLCG2 fragment

PLCG; FCAS; PLC-gamma; PLCG2; APLAID; FCAS3; PLC-IV; PLC-gamma-2; phospholipase C gamma 2

A609

Unconjugated

WB

Signal Transduction; Cardiovascular; Metabolism

Protein A purified

1 mg/mL

WB 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/kt9GtUgl

148 kDa

148 kDa

IgG, κ