Recombinatie PM2 monoklonaal antilichaam
Gecertificeerd

Recombinatie PM2 monoklonaal antilichaam

Catalog #: AN301379L
Maat: 100 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100

Technische Specificaties

Background

The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA (X) 2E (X) 4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease.

Abbreviation

PMS2

UniProt

P54278

Host

• Rabbit

Reactivity

Human

Immunogen

Recombinant Human PMS2 protein

Target

MLH; PMS; PMSL; HNPCC; PMS2; HNPCC4; MLH4; PMS2CL; PMSL2

Clonality

• Monoclonal

• Recombinant

Clone

6F12

Conjugation

Unconjugated

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:500-5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/rCjHZ43J

Calculated Molecular Weight

96 kDa

Observed Molecular Weight

110 kDa

Isotype

IgG, κ

Beschrijving

Recombinatie PM2 monoklonaal antilichaam Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamRecombinatie PM2 monoklonaal antilichaam
Categorie
Beschikbare grootte100 µL
CatalogusnummerAN301379L