Recombinatie RXRA monoklonaal antilichaam

Retinoid X receptor α (RXRA) is the founding RXR family member and is predominantly expressed in the liver, kidney, epidermis, intestine, and a variety of tissues. Knockout of the murine rxrα gene results in embryonic lethality tentatively due to myocardial hypoplasia, which demonstrates the importance of RXRA in retinoid signaling in vivo. Biochemical evidence suggests that RXRA transcriptional activity is post-translationally regulated through the Ras-Raf-MAPK signaling cascade. MAPK-dependent phosphorylation of RXRα directly abrogates the ability of RXRA to associate with nuclear receptor coactivators.

RXRA

P19793

Human

Recombinant human RXRA fragment

NR2B; NR2B1; RXRA; Retinoid X receptor alpha

A659

Unconjugated

WB; IF

Epigenetics and Nuclear Signaling; Signal Transduction; Cancer; Metabolism

Protein A purified

1 mg/mL

WB 1:1000; IF 1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/HBmvdCrc

51 kDa

56 kDa

IgG, κ