Recombinatie SIN3A monoklonaal antilichaam

OnBackground Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYConcogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperativelywith OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for thetranscriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for corticalneuron differentiation and callosal axon elongation.

SIN3A

Q96ST3

Human; Rat; Mouse

Peptide. This information is proprietary to PTMab.

SIN3A; WITKOS

A779

Unconjugated

WB; IHC; IP

Epigenetics and Nuclear Signaling; Cancer; Metabolism

Protein A purified

1 mg/mL

WB 1:1000-1:2000; IHC 1:100-1:1000; IP 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/Edc0UVjG

145 kDa

150 kDa

IgG, κ