Recombinatie SIRT2- monoklonaal antilichaam

NAD-dependent protein deacetylase sirtuin-2 (SIRT2) is a NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. SIRT2 participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. SIRT2 plays a major role in the control of cell cycle progression and genomic stability. It also functions in the antephase checkpoint preventing precocious mitotic entry in response to microtubule stress agents, and hence allowing proper inheritance of chromosomes.

SIRT2

Q8IXJ6

Human; Rat; Mouse

Recombinant human SIRT2 fragment

SIR; SIRT; sirtuin; SIRT2; SIR2; SIR2L; SIR2L2; sirtuin 2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2; Sirtuin type 2

A435

Unconjugated

WB; IHC

Epigenetics and Nuclear Signaling; Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/o3ZeozuT

43 kDa

36, 43 kDa

IgG, κ