Recombinatie SOX17 monoklonaal antilichaam

SRY-related high mobility group box (SOX) proteins comprise a large family of widely conserved transcription factors. SOX proteins do not directly mediate transcription, but require binding partners that regulate their ability to mediate transcription of target genes that control cell fate determination and development .Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing β-catenin signaling. Mutation in the corresponding Sox17 gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects.

SOX17

Q9H6I2

Human

Recombinant human SOX17 fragment

VUR; SOX; VUR3; SOX17

A676

Unconjugated

WB; IHC

Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology

Protein A purified

1 mg/mL

WB 1:1000-1:2000; IHC 1:100-1:200

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/UvyByl80

55 kDa

55 kDa

IgG, κ